UTP is a nucleotide that
is a substrate for RNA polymerase in synthesis of RNA. It is also
a precursor of CTP in de novo synthesis of pyrimidine nucleotides
(Figure 22.10)
UTP is a nucleotide that
is a substrate for RNA polymerase in synthesis of RNA. It is also
a precursor of CTP in de novo synthesis of pyrimidine nucleotides
(Figure 22.10)
UTP + ATP + Gln <=> CTP + ADP + Glu + Pi (catalyzed by CTP synthetase)
UTP is a also used to activate sugars for polysaccharide synthesis, such as the reaction below, which activated glucose in glycogen biosynthesis:
Glucose-1-Phosphate + UTP <=> UDP-Glucose + PPi (catalyzed by UDP-Glucose Pyrophosphorylase)