F6P is a phosphorylated form of fructose commonly found in cells. F6P is an intermediate in glycolysis, gluconeogenesis, the pentose phosphate pathway, and the Calvin cycle. F6P is a substrate in biosynthesis of the important allosteric factor regulating glycolysis, fructose-2,6-bisphosphate and is also an important precursor of amino sugars (last enzyme below).

Enzymes whose activity includes F6P:

Phosphoglucoisomerase

Phosphofructokinase

Fructose 1,6 Bisphosphatase

Fructose 2,6 Bisphosphatase

Transaldolase

Glutamine:Fructose-6-Phosphate Amidotransferase