Deoxyadenosine Triphosphate (dATP)

dATP is a substrate for DNA polymerase in synthesis of DNA. It is produced from dADP by nucleoside diphosphokinase catalysis as follows:

dADP + ATP <=> dATP + ADP

dATP is also implicated in severe combined immune deficiency (SCID) (see here).


See also: Nucleotides