Nucleoside Kinases

Nucleoside kinases are a class of enzymes that catalyze the phosphorylation of nucleosides to make nucleoside monophosphates (Figure 22.2) as part of nucleotide biosynthetic salvage pathways. ATP provides the energy and phosphate for the reaction. Example enzymes include thymidine kinase, deoxycytidine kinase, and deoxyguanosine kinase.


See also: Salvage Routes to Deoxyribonucleotide Synthesis