Dihydrouracil is an intermediate in catabolism of pyrimidines (Figure 22.11). It is formed by reduction
of uracil (Figure
22.11) and then converted to
-ureidopropionic
acid as shown in the reaction that follows:
Dihydrouracil + H2O <=>
-Ureidopropionic Acid (catalyzed by Hydropyrimidine Hydratase)