Dihydroorotate is an intermediate in de novo pyridine biosynthesis.
It is synthesized from carbamoyl aspartate (as shown in the reaction
that follows) and then converted to orotate
(reaction 4, Figure 22.10).
Dihydroorotate is an intermediate in de novo pyridine biosynthesis.
It is synthesized from carbamoyl aspartate (as shown in the reaction
that follows) and then converted to orotate
(reaction 4, Figure 22.10).
Carbamoyl Aspartate <=> Dihydroorotate + H2O (catalyzed by Dihydroorotase)