Adenylosuccinate is an intermediate in de novo biosynthesis of AMP (Figure 22.6). Adenylosuccinate is involved in the reactions shown below.
Adenylosuccinate is an intermediate in de novo biosynthesis of AMP (Figure 22.6). Adenylosuccinate is involved in the reactions shown below.
1. IMP + Aspartic Acid + GTP <=> Adenylosuccinate + GDP + Pi (catalyzed by Adenylosuccinate Synthetase)
2. Adenylosuccinate <=> Fumarate + AMP (catalyzed by Adenylosuccinate Lyase)
See also: De Novo Biosynthesis of Purine Nucleotides