A key intermediate in synthesis of
virtually all aromatic compounds in the cells is shikimic acid.
These include phenylalanine,
tyrosine, tryptophan,
p-aminobenzoic acid, and p-hydroxybenzoic acid.
A key intermediate in synthesis of
virtually all aromatic compounds in the cells is shikimic acid.
These include phenylalanine,
tyrosine, tryptophan,
p-aminobenzoic acid, and p-hydroxybenzoic acid.
The unbranched pathways from erythrose-4-phosphate and phosphoenolpyruvate through shikimic acid to chorismate is shown in Figure 21.13. The sixth reaction of the shikimic acid pathway is inhibited specifically by glyphosate, which is the active ingredient in the broad spectrum herbicide known as RoundupTM.