Figure 21.12 provides an overview of the biosynthesis of aromatic
amino acids and histidine. All of the carbons in phenylalanine
and tyrosine are derived from erythrose-4-phosphate and phosphoenolpyruvate.
A key intermediate in synthesis of virtually all aromatic compounds
(including p-aminobenzoic acid) in plant and bacterial
cells is shikimic acid. Shikimic acid gives rise to chorismate
(Figure 21.13), which is a precursor
of p-hydroxybenzoic acid (Figure
21.14). p-Hydroxybenzoic acid, in turn, can be
converted to coenzyme Q.