-Aspartyl-Phosphate
-Aspartyl-Phosphate
-Aspartyl-phosphate is an intermediate in the conversion of aspartate
to homoserine (see here) in the pathway leading to biosynthesis
of threonine, isoleucine,
and methionine.
1. Aspartate + ATP <=>
-Aspartyl-Phosphate + ADP
(catalyzed by Aspartokinase)
2. -Aspartyl Phosphate + NADPH +
H+ <=> Aspartic
Semialdehyde + NADP+ + Pi (catalyzed by Aspartate Semialdehyde Dehydrogenase).
See also: Metabolism
of Serine, Glycine, and Threonine,
Metabolism of Valine, Leucine, Isoleucine,
and Lysine, Metabolism of Sulfur-Containing
Amino Acids