Vitamin K is found in plants as phylloquinone
(vitamin K1)
and in animals as menaquinone (vitamin K2). Vitamin K2 is essential for the carboxylation
of glutamate residues in certain proteins, to give
-carboxyglutamate.
This modification allows the protein to bind calcium, an essential
event in the blood clotting cascade. Carboxylation of glutamate
is also important in other proteins involved in the mobilization
or transport of calcium.