CDP-diacylglycerol is an important intermediate in biosynthesis of the
glycerophospholipids (see Figures 19.2,
19.4, 19.8),
leading to synthesis of phosphatidylserine,
phosphatidylethanolamine,
phosphatidylglycerol, cardiolipin, phosphatidylinositol,
and phosphatidylcholine.
CDP-diacylglycerol is made by combining phosphatidic acid and CTP (Figure 19.3). In each of the glycerophospholipid reaction pathways from CDP-diacylglycerol, CMP is split from the molecule in order to put on the serine, ethanolamine, glycerol, or inositol moieties.
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