-Ketoacyl-ACP

-Ketoacyl-ACP is a metabolite in fatty acid biosynthesis. It participates in the reactions as follows (Figure 18.27):

1. Acetyl-ACP + Malonyl-ACP <=> -Ketoacyl-ACP + ACP + CO2 (catalyzed by -Ketoacyl-ACP Synthase)

2. -Ketoacyl-ACP + NADPH + H+  <=> D-3-Hydroxyacyl-ACP +  NADP+ (catalyzed by -Ketoacyl-ACP Reductase)

See also: Fatty Acid Biosynthesis Strategy, Fatty Acid Synthase, Fatty Acids, Palmitate Synthesis from Acetyl-CoA, Synthesis of Long Chain Fatty Acids

INTERNET LINK: Fatty Acid Biosynthesis