Sialic Acid

Sialic acid is a name for a group of compounds derived from or related to N-acetylneuraminic acid. Sialic acids are found in glycoproteins, gangliosides, and glycolipids. Sialic acid is activated for addition to a growing glycoprotein by reaction with CTP as follows:

CTP + Sialic acid <=> CMP-Sialic Acid


See also: Glycoproteins, Figure 9.29, Figure 16.14, Figure 19.14