Fumarate
Fumarate is an intermediate of the citric
acid cycle and the glyoxylate cycle.
produced by action of the enzyme succinate dehydrogenase on succinate.
FADH2 is produced
from FAD in the reaction. Fumarate is converted to L-malate
by addition of water to the molecule catalyzed by the enzyme fumarate
hydratase.
See also: Enzymes
of the Citric Acid Cycle, Intermediates
of the citric acid cycle, Pathway
of the citric acid cycle, Table 4.1,
Succinate Dehydrogenase, Fumarate Hydratase
INTERNET LINKS:
1. Glyoxylate
Cycle Metabolism
2. Citric
Acid Cycle
3. Urea
Cycle and Metabolism of Amino Groups