L-Homoserine
L-Homoserine is found in many tissues as a intermediate in amino
acid metabolism, including threonine,
isoleucine, and methionine.
Catabolism of aspartate to homoserine is shown here.
The biosynthetic pathway from homoserine to methionine
is shown in Figure 21.6.
Aspartic
Semialdehyde + NADPH +
H+ <=> Homoserine + NADP+ (catalyzed by homoserine
dehydrogenase).
See also: Amino
Acids Not In Proteins, Metabolism
of Serine, Glycine, and Threonine, Metabolism
of Valine, Leucine, Isoleucine, and Lysine, Metabolism
of Sulfur-Containing Amino Acids
INTERNET LINK: Gly,
Ser, Thr Metabolism