| Dates |
Day |
Chapter |
Read Before Class |
Comments |
Time, Love, Memory |
| Aug 26 |
M |
Intro.; email your thoughts |
N. A. |
|
Reading List |
| Aug 28 |
W |
10: What's wrong with my child? |
277 - 284 |
diagnose |
Chapter 1 |
| Aug 30 |
F |
10: What's wrong with my child? |
284 - 290 |
refine; stop after MM 10.2 |
Chapter 2 |
| Sep 2 |
M |
10: What's wrong with my child? |
290 - 303 |
expand |
Chapter 2 |
| Sep 4 |
W |
11: Why can't I lose weight? |
305 - 315 |
simple fix |
Chapter 3 |
| Sep 6 |
F |
11: Why can't I lose weight?
12: Why can't we cure more people? |
315 - 319
320 - 329 |
complications
designer drugs |
Chapter 3 |
| first draft |
M |
Pilot Web Page |
Put it online |
Due Monday Sep 9, 11:30 am |
- |
| Sep 9 |
M |
1: What is genomics? |
1 - 9 |
defining genomes |
Chapter 4 |
| Sep 11 |
W |
1: What is genomics? |
9 - 16 |
protein function/s |
Chapter 4 |
| Sep 13 |
F |
1: Lessons from draft human genome? |
17 - 24 |
straight up analysis |
Chapter 5 |
| Sep 16 |
M |
1: Lessons from draft human genome?
2: What is the origin of eukaryotes? (part 1) |
24 - 28
30 - 35 |
complications
prokryotes to eukaryotes |
Chapter 5 |
| revised page |
W |
First Web Page |
Trait and Gene |
Due Wednesday Sep 18, 2:00 pm |
- |
| Sep 18 |
W |
2: Where are the missing links? |
35 - 41 |
endosymbionts and weak pathogens |
Chapter 6 |
| Sep 20 |
F |
2: What is the origin of humans?
2: How can genomics help fight bioterrorism? |
41 - 49 |
human evolution
weapon detection |
Chapter 6 |
| Sep 23 |
M |
2: How old is this DNA? |
49 - 57 |
forensics |
Chapter 7 |
| Sep 25 |
W |
2: Can we improve medical treatments? |
57 - 66 |
biomedical applications |
Chapter 7 |
| Sep 25-27 |
. |
FIRST EXAM |
TAKE HOME |
DUE FRIDAY 11:30 am |
- |
| Sept 27 |
F |
TEST RECOVERY |
TLM DISCUSSIONS |
What is the foundation of genomics? |
Chapters 1-7 |
| Sept 30 |
M |
3: What drives environmental diversity? |
69 - 79 |
small changes with big consequences |
Chapter 8 |
| Oct 2 |
W |
3: What are SNPs? |
80 - 89 |
functional impact of human diversity |
Chapter 9 |
| Oct 4 |
F |
3: Is death a genetically determined trait? |
89 - 93 |
the final phenotype |
Chapter 10 |
| YFYG |
M |
Your Favorite Yeast Genes |
one annotated & one not annotated |
Due Monday Oct 7, 2:00 pm |
- |
| Oct 7 |
M |
3: What are the ethical implications? |
93 - 102 |
ELSI and you |
Chapter 11 |
| Oct 9 |
W |
4: What are DNA microarrays? |
105 - 117 |
bad beer; stop after MM 4.3 |
Chapter 11 |
| Oct 11 |
F |
4: What are DNA microarrays? |
117 - 124 |
bad beer; stop at "stressed out" |
Chapter 12 |
| Oct 14 |
M |
Fall Break |
ZZZZZZZ |
No Class |
|
| Oct 16 |
W |
4: What can you learn from them? |
124-135 |
streesed out yeast |
Chapter 13 |
| Oct 18 |
F |
5: Can microarrays diagnose cancer? |
137 - 141 |
lymphoma |
Chapter 14 |
| Oct 21 |
M |
5: Do microarrays always work? |
141 - 146 |
breast cancer and instability |
Chapter 15 |
| Oct 23 |
W |
catch up time? |
|
|
Chapter 15 |
| YFYO |
F |
Your Favorite Yeast Expression |
one annotated & one not annotated |
Due Friday Oct 25, 2:00 pm |
- |
| Oct 25 |
F |
5: Why is this vaccine less effective now? |
146 - 149 |
TB vaccine |
Chapter 16 |
| Oct 28 |
M |
5: How does this drug work? |
149 - 154 |
yeast on drugs |
Chapter 16 |
| Oct 30 |
W |
5: Can microarrys analyze obesity? |
154 - 158 |
fat and chips |
Chapter 17 |
| Oct 30-Nov 1 |
. |
SECOND EXAM |
TAKE HOME |
DUE FRIDAY 11:30 am |
- |
| Nov 1 |
F |
TEST RECOVERY |
TLM DISCUSSIONS |
What is the role of a single gene? |
Chapter 1-16 |
| Nov 4 |
M |
6: What do all these proteins do? |
161 - 170 |
knockout genes |
Chapter 17 |
| Nov 6 |
W |
6: Does a protein's shape reveal its function? |
170 - 176 |
structural proteomics |
Chapter 17 |
| Nov 8 |
F |
6: Which proteins interact with each other? |
176 - 183 |
protein networks |
Chapter 17 |
| Nov 11 |
M |
6: Which proteins are present? |
183 - 189 |
protein identificaion by MS/MS |
Chapter 18 |
| Nov 13 |
W |
6: How much protein is present? |
189 - 196 |
relative quantification |
Chapter 18 |
| YFYP |
F |
Your Favorite Yeast Protein |
one annotated & one not annotated |
Due Friday Nov 15, 2:00 pm |
- |
| Nov 15 |
F |
6: Can we measure single proteins? |
196 - 202 |
single proteins and metabolomics |
Chapter 18 |
| Nov 18 |
M |
7: Are genes hardwired? |
205 - 218 |
Endo16 |
Other Opinions |
| Nov 20 |
W |
7: What controls amount, location and timing? |
218 - 231 |
Endo16 |
Other Opinions |
| Nov 22 |
F |
8: How do genes make choices? |
232 - 238 |
toggle switches |
Other Opinions |
| Nov 25 |
M |
8: Can we build genetic toggle switches? |
238 - 244 |
synthetic toggle switches |
Other Opinions |
| Nov 27 |
W |
Thanksgiving |
Eat |
No Class |
- |
| Nov 29 |
F |
Thanksgiving |
Sleep |
No Class |
- |
| Dec 2 |
M |
8: How is long-term poteniation established? |
244 - 252 |
learning |
Other Opinions |
| Dec 4 |
W |
8: Can we model learning? |
252 - 257 |
more learning |
Chapter 19 |
| Dec 6 |
F |
8: Can we understand complex circuits? |
257 - 263 |
cancer circuits; T7 genome order |
Chapter 19 |
| Dec 9 |
M |
9: Can systems biology reveal new properties? |
265 - 274 |
systems biology |
Chapter 19 |
| Dec 11 |
W |
9: How have you changed this semester? |
Summary |
final words; have you changed? |
Chapter 19 |
| Dec 11 |
W |
Exams Due Dec. 18, 2 pm |
Course Evaluation Fellowships |
Free will? Was Calvin right? |
many others to read now |
